No word yet on whether or not Xbox Music is breaking out of its Windows 8 prison
You'll also be able to take any website that contains streaming music and share it to the updated app to create an instant playlist of all those songs right inside Xbox Music.
Source: http://gizmodo.com/no-word-yet-on-whether-or-not-xbox-music-is-breaking-ou-586653025
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June 26, 2013 ? A new study helps explain how parts of the brain maintain their delicate balance of zinc, an element required in minute but crucial doses, particularly during embryonic development.
The study, led at the Marine Biological Laboratory (MBL) by Mark Messerli in collaboration with scientists from the University of California, Davis, shows that neural cells require zinc uptake through a membrane transporter referred to as ZIP12.. If that route is closed, neuronal sprouting and growth are significantly impaired and is fatal for a developing embryo. Their discovery was published in the Proceedings of the National Academy of Sciences.
"This particular transporter is an essential doorway for many neurons in the central nervous system," explains Messerli. "You knock out this one gene, this one particular pathway for the uptake of zinc into these cells, and you essentially prevent neuronal outgrowth. That's lethal to the embryo."
Previously, scientists thought that zinc could use more than one pathway to enter the cell during early brain development. Some other elements, like calcium, enjoy such luxury of multiple options.
Knocking out ZIP12, affected several critical processes in the brain, the scientists found. For example, frog embryos were unable to develop their neural systems properly. Additionally, neurons had trouble reaching out to connect to other neurons; their extensions were both shorter and fewer in number than normal.
"We were surprised that ZIP12 was required at such an early and critical stage of development," said Winyoo Chowanadisai, a researcher in nutrition at the University of California at Davis and visiting scientist in the Cellular Dynamics Program at the MBL. Dr. Chowanadisai was the first on the team to realize that ZIP12 is expressed in such abundance in the brain."This study also reinforces the importance of periconceptional and prenatal nutrition and counseling to promote health during the earliest stages of life."
ZIP12 is part of a larger family of transporters involved in the movement of metal ions from outside the cell. Other reports showed that simultaneously blocking 3 other transporters in the family -- including ZIP1, 2, and 3 -- had no major effects on embryonic development.
Zinc is needed for healthy neural development, helping the brain to learn and remember new information. However, too much zinc can also be problematic.
The research team is investigating the implications of their results on processes like embryonic brain development and wound healing.
"[The result] was not expected," said Messerli, a physiologist in the MBL's Bell Center for Regenerative Biology and Tissue Enginering and Cellular Dynamics Program. ""We found that zinc uptake through ZIP12 is a regulatory point for neuronal growth, required for development and possibly required for learning and memory throughout life. We want to elucidate the downstream targets that zinc is affecting. That's the next exploration."
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/7oxtNlIxpwk/130626162822.htm
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WASHINGTON (AP) ? The bizarre journey of Edward Snowden is far from over. After spending a night in Moscow's airport, the former National Security Agency contractor ? and admitted leaker of state secrets ? was expected to fly to Cuba and Venezuela en route to possible asylum in Ecuador.
Snowden, also a former CIA technician, fled Hong Kong on Sunday to dodge U.S. efforts to extradite him on espionage charges. Ecuador's Foreign Minister Ricardo Patino said his government had received an asylum request, adding Monday that the decision "has to do with freedom of expression and with the security of citizens around the world." The anti-secrecy group WikiLeaks also said it would help Snowden.
Ecuador has rejected the United States' previous efforts at cooperation, and has been helping WikiLeaks founder, Julian Assange, avoid prosecution by allowing him to stay at its embassy in London.
Snowden gave documents to The Guardian and The Washington Post newspapers disclosing U.S. surveillance programs that collect vast amounts of phone records and online data in the name of foreign intelligence, often sweeping up information on American citizens. Officials have the ability to collect phone and Internet information broadly but need a warrant to examine specific cases where they believe terrorism is involved.
Snowden had been in hiding for several weeks in Hong Kong, a former British colony with a high degree of autonomy from mainland China. The United States formally sought Snowden's extradition from Hong Kong to face espionage charges but was rebuffed; Hong Kong officials said the U.S. request did not fully comply with their laws.
The Justice Department rejected that claim, saying its request met all of the requirements of the extradition treaty between the U.S. and Hong Kong. During conversations last week, including a phone call Wednesday between Attorney General Eric Holder and Hong Kong Secretary for Justice Rimsky Yuen, Hong Kong officials never raised any issues regarding sufficiency of the U.S. request, a Justice representative said.
The United States was in touch through diplomatic and law enforcement channels with countries that Snowden could travel through or to, reminding them that Snowden is wanted on criminal charges and reiterating Washington's position that Snowden should only be permitted to travel back to the U.S., a State Department official said. Snowden's U.S. passport has been revoked.
U.S. officials spoke on condition of anonymity because they were not authorized to publicly discuss the case.
An unidentified Aeroflot airline official was cited by Russia's state ITAR-Tass news agency and Interfax as saying Snowden was on the plane that landed Sunday afternoon in Moscow. The Russian report said Snowden intended to fly to Cuba on Monday and then on to Caracas, Venezuela.
The White House was hoping to stop Snowden before he left Moscow.
Caitlin Hayden, a spokeswoman for the National Security Council, said, "Given our intensified cooperation after the Boston marathon bombings and our history of working with Russia on law enforcement matters ? including returning numerous high-level criminals back to Russia at the request of the Russian government ? we expect the Russian government to look at all options available to expel Mr. Snowden back to the U.S. to face justice for the crimes with which he is charged."
Still, the United States is likely to have problems interrupting Snowden's passage. The United States does not have an extradition treaty with Russia, but does with Cuba, Venezuela and Ecuador. Even with an extradition agreement though, any country could give Snowden a political exemption.
The likelihood that any of these countries would stop Snowden from traveling on to Ecuador seemed remote. While diplomatic tensions have thawed in recent years, Cuba and the United States are hardly allies after a half-century of distrust. Another country that could see Snowden pass through, Venezuela, could prove difficult, as well. Former President Hugo Chavez was a sworn enemy of the United States and his successor, Nicolas Maduro, earlier this year called President Barack Obama "grand chief of devils." The two countries do not exchange ambassadors.
Snowden's options aren't numerous, said Assange's lawyer, Michael Ratner.
"You have to have a country that's going to stand up to the United States," Ratner said. "You're not talking about a huge range of countries here."
It also wasn't clear Snowden was finished disclosing highly classified information.
Snowden has perhaps more than 200 sensitive documents, Sen. Dianne Feinstein, chairwoman of the Senate Intelligence Committee, said on CBS' "Face the Nation."
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Associated Press White House Correspondent Julie Pace and Associated Press writers Matthew Lee and Frederic J. Frommer in Washington, Lynn Berry in Moscow, Kevin Chan in Hong Kong and Sylvia Hui in London contributed to this report.
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Follow Philip Elliott on Twitter: http://www.twitter.com/philip_elliott
Source: http://news.yahoo.com/nsa-leaker-snowden-expected-fly-cuba-050842508.html
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